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Minimally expanded breast cancer tumor-infiltrating-lymphocytes provide guidance for therapeutic selection

Abstract: The analysis of tumor-infiltrating lymphocytes often requires techniques that expand their numbers, potentially introducing bias. To address this, we performed a…

Date: 2025-11-26

Long-term outcomes and patterns of failure after empiric SBRT for presumed early-stage lung tumors

Abstract: Stereotactic body radiation therapy (SBRT) is the established standard of care for medically inoperable early-stage non-small cell lung cancer (ES-NSCLC). When a biopsy…

Date: 2025-11-25

Comparative efficacy of r-hFSH Alfa + r-LH versus r-hFSH delta + hMG in poor ovarian responders

Abstract: Poor ovarian response (POR) remains a major limitation in assisted reproductive medicine. Direct comparisons between r-hFSH alfa + r-LH and r-hFSH delta + hMG in this…

Date: 2025-11-25

Association between the age-to-serum albumin ratio and all-cause mortality in patients with acute myocardial infarction: a retrospective cohort study

Abstract: Acute myocardial infarction (AMI) remains a predominant cause of cardiovascular death, necessitating accurate risk stratification. Existing risk scores like the ACEF…

Date: 2025-11-25

Clinical outcomes of monitored anesthesia care vs. general anesthesia in transfemoral transcatheter aortic valve implantation: a single-center retrospective study

Abstract: Transcatheter aortic valve implantation (TAVI) has become a preferred treatment for severe aortic stenosis in high-risk patients. In China, general anesthesia (GA)…

Date: 2025-11-25

Correlation of body compositions and bone mineral density in postmenopausal women with different body mass index

Abstract: The association between obesity and bone mineral density (BMD) is controversial. Body composition parameters have been found to be strongly correlated with BMD. Body…

Date: 2025-11-25

Exploring the relationship of triglyceride to high-density lipoprotein cholesterol and the triglyceride-glucose index with white matter hyperintensities in individuals with type 2 diabetes: a cross-sectional analysis

Abstract: Previous studies have shown that the triglyceride-glucose index (TyG) is associated with white matter hyperintensities (WMH) in a healthy population, acting as a marker…

Date: 2025-11-25

The predictive value of 24-hour urinary calcium for kidney stone risk in primary hyperparathyroidism: insight from a retrospective study of parathyroid adenoma cases

Abstract: Primary hyperparathyroidism (PHPT) is associated with an increased risk of kidney stones. However, the clinical utility of 24-hour urinary calcium (24h-UCa) as a…

Date: 2025-11-25

Association between the triglyceride-glucose index and carotid plaque progression in patients with type 2 diabetes mellitus: a retrospective cohort study

Abstract: The triglyceride-glucose (TyG) index is a novel marker of insulin resistance associated with carotid vascular disease; however, its role in type 2 diabetes mellitus…

Date: 2025-11-25

Association between SQSTM1 dysregulation and risk in alopecia areata: a Mendelian randomization study

Abstract: Alopecia areata (AA) is an autoimmune disease typified by nonscarring hair loss. It manifests as a heterogeneous disorder with diverse clinical presentations and…

Date: 2025-11-25