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Catatonia and melancholia interface: exploring a new paradigm for evaluation and treatment. A case series and literature review

Abstract: Background: Catatonia has been increasingly associated with mood disorders and is recognized as a specifier in the DSM-5 and DSM-5-TR. The DSM-5-TR recognizes…

Date: 2024-03-27

Intratumor tertiary lymphatic structure evaluation predicts the prognosis and immunotherapy response of patients with colorectal cancer

Abstract: Background: Immune checkpoint therapy, involving the programmed cell death 1 (PD-1) monoclonal antibody, has revolutionized the treatment of cancer. Tertiary lymphatic…

Date: 2024-03-27

Deep analysis of skin molecular heterogeneities and their significance on the precise treatment of patients with psoriasis

Abstract: Background: Psoriasis is a highly heterogeneous autoinflammatory disease. At present, heterogeneity in disease has not been adequately translated into concrete treatment…

Date: 2024-03-27

Associations of perchlorate, nitrate, and thiocyanate exposure with arthritis and inflammation indicators in young and middle-aged adults, NHANES 2005-2016

Abstract: Background: Perchlorates, nitrates, and thiocyanates are prevalent environmental chemicals. Their potential association with arthritis remains unexplored. This study…

Date: 2024-03-27

Staff perspectives on poor mental health in secondary school students: an increasing problem handled with insufficient resources

Abstract: Introduction: An increasing number of schools are recognizing the importance of addressing students' mental health based on the association with educational outcomes and…

Date: 2024-03-27

Comprehensive molecular and cellular characterization of endoplasmic reticulum stress-related key genes in renal ischemia/reperfusion injury

Abstract: Background: Renal ischemia-reperfusion injury (RIRI) is an inevitable complication in the process of kidney transplantation and lacks specific therapy. The study aims to…

Date: 2024-03-27

Efficacy of neuroendoscopic-assisted surgery in the management of symptomatic sacral perineural (Tarlov) cysts: a technical report

Abstract: Introduction: The Tarlov cysts are pathological enlargements of the cerebrospinal fluid spaces between the endoneurium and perineurium, which can cause intolerable…

Date: 2024-03-27

Effectively communicating with local policymakers: a randomized trial of policy brief dissemination to address obesity

Abstract: Introduction: Evidence-based policies are a powerful tool for impacting health and addressing obesity. Effectively communicating evidence to policymakers is critical to…

Date: 2024-03-27

Comparative efficacy of anthropometric indices in predicting 10-year ASCVD risk: insights from NHANES data

Abstract: Background: Cardiovascular diseases remain a leading cause of morbidity and mortality worldwide. Accurately predicting the 10-year risk of Atherosclerotic Cardiovascular…

Date: 2024-03-27