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Socioeconomic inequality in timing of ANC visit among pregnant women in Ethiopia, 2019

Abstract: Background: Antenatal care (ANC) remains an invaluable approach to preventive care for ensuring maternal and infant health outcomes. Women in sub-Saharan Africa tend to…

Date: 2024-03-27

Prediction of intraoperative red blood cell transfusion in valve replacement surgery: machine learning algorithm development based on non-anemic cohort

Abstract: Background: Our study aimed to develop machine learning algorithms capable of predicting red blood cell (RBC) transfusion during valve replacement surgery based on a…

Date: 2024-03-27

SKAP2 acts downstream of CD11b/CD18 and regulates neutrophil effector function

Abstract: Background: The importance of CD11b/CD18 expression in neutrophil effector functions is well known. Beyond KINDLIN3 and TALIN1, which are involved in the induction of…

Date: 2024-03-27

Comparison of SARS-CoV-2 spike-specific IgA and IgG in nasal secretions, saliva and serum

Abstract: Introduction: Several novel vaccine platforms aim at mucosal immunity in the respiratory tract to block SARS-CoV-2 transmission. Standardized methods for mucosal sample…

Date: 2024-03-27

Long-term efficacy of left bundle branch pacing and biventricular pacing in patients with heart failure complicated with left bundle branch block

Abstract: Background: Left bundle branch pacing (LBBP) can physiologically correct complete left bundle branch block (CLBBB), and has become the best alternative to biventricular…

Date: 2024-03-27

Multiple environmental antigens may trigger autoimmunity in psoriasis through T-cell receptor polyspecificity

Abstract: Introduction: Psoriasis is a T-cell mediated autoimmune skin disease. HLA-C*06:02 is the main psoriasis-specific risk gene. Using a V?3S1/V?13S1 T-cell receptor (TCR)…

Date: 2024-03-27

Causality between allergic diseases and kidney diseases: a two-sample Mendelian randomization study

Abstract: Background: Evidence from observational studies and clinical trials suggests that the allergic diseases (ADs) are associated with kidney diseases (KDs). However, the…

Date: 2024-03-27

High hypoxia status in pancreatic cancer is associated with multiple hallmarks of an immunosuppressive tumor microenvironment

Abstract: Introduction: Pancreatic ductal adenocarcinoma (PDAC), the most common form of pancreatic cancer, is a particularly lethal disease that is often diagnosed late and is…

Date: 2024-03-27

Structure-guided engineering and molecular simulations to design a potent monoclonal antibody to target aP2 antigen for adaptive immune response instigation against type 2 diabetes

Abstract: Introduction: Diabetes mellitus (DM) is recognized as one of the oldest chronic diseases and has become a significant public health issue, necessitating innovative…

Date: 2024-03-27