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Exploring the joint potential of inflammation, immunity, and receptor-based biomarkers for evaluating ME/CFS progression

Abstract: Background: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating chronic condition with no identified diagnostic biomarkers to date. Its…

Date: 2024-01-16

Impact of lockdown on children with type-1 diabetes: returning to the community was associated with a decrease in HbA1c

Abstract: Background: In March 2020, a 2-month lockdown of the entire population has been declared in France to limit the spread of COVID-19. Sudden changes in daily life can…

Date: 2024-01-16

Expression of secreted frizzled-related proteins in acute aortic dissection patients and the effects on prognosis

Abstract: Background: Secreted frizzled-related proteins (SFRPs) were reported to be involved in cardiovascular diseases. This study aimed to observe plasma SFRP levels in acute…

Date: 2024-01-16

Exploration of macromolecular phenotype of human skeletal muscle in diabetes using infrared spectroscopy

Abstract: Introduction: The global burden of diabetes mellitus is escalating, and more efficient investigative strategies are needed for a deeper understanding of underlying…

Date: 2024-01-16

The transcription factor VAX1 in VIP neurons of the suprachiasmatic nucleus impacts circadian rhythm generation, depressive-like behavior, and the reproductive axis in a sex-specific manner in mice

Abstract: Background: The suprachiasmatic nucleus (SCN) within the hypothalamus is a key brain structure required to relay light information to the body and synchronize cell and…

Date: 2024-01-16

Development and performance of the c4c national clinical trial networks for optimizing pediatric trial facilitation

Abstract: Introduction: The high failure rate of industry-driven pediatric clinical trials leads to insufficient timely labeling of drugs in children and a lack of scientific…

Date: 2024-01-16

In-hospital and 1-year outcomes of patients without modifiable risk factors presenting with acute coronary syndrome undergoing PCI: a Sex-stratified analysis

Abstract: Aim: A considerable proportion of patients admitted with acute coronary syndrome (ACS) have no standard modifiable cardiovascular risk factors (SMuRFs: hypertension,…

Date: 2024-01-16

Interrater variability of ML-based CT-FFR during TAVR-planning: influence of image quality and coronary artery calcifications

Abstract: Background: Coronary computed tomography angiography (cCTA) can effectively exclude CAD, e.g. prior to TAVR, but remains limited by its specificity. CT-FFR may mitigate…

Date: 2024-01-16

Appearance of tolerance-induction and non-inflammatory SARS-CoV-2 spike-specific IgG4 antibodies after COVID-19 booster vaccinations

Abstract: Background: Understanding the characteristics of the humoral immune responses following COVID-19 vaccinations is crucial for refining vaccination strategies and…

Date: 2024-01-16