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HELIOS-expressing human CD8 T cells exhibit limited effector functions

Abstract: Introduction: The transcription factor HELIOS is primarily known for its expression in CD4 regulatory T cells, both in humans and mice. In mice, HELIOS is found in…

Date: 2024-01-16

Development and optimization of AI algorithms for wrist fracture detection in children using a freely available dataset

Abstract: Introduction: In the field of pediatric trauma computer-aided detection (CADe) and computer-aided diagnosis (CADx) systems have emerged offering a promising avenue for…

Date: 2024-01-16

Ameliorated chest drain wound closure in patients undergoing uniportal thoracoscopic pulmonary resection

Abstract: Background: Although uniportal video-assisted thoracoscopic surgery (VATS) has been performed for a wide array of thoracic diseases, unsightliness and poor wound healing…

Date: 2024-01-16

A nomogram model to predict the portal vein thrombosis risk after surgery in patients with pancreatic cancer

Abstract: Background: Portal vein thrombosis (PVT) is a common postoperative complication in patients with pancreatic cancer (PC), significantly affecting their quality of life…

Date: 2024-01-16

Association between mortality and critical events within 48 hours of transfer to the pediatric intensive care unit

Abstract: Introduction: Critical deterioration in hospitalized children, defined as ward to pediatric intensive care unit (PICU) transfer followed by mechanical ventilation (MV)…

Date: 2024-01-16

Discovery of plasma proteome markers associated with clinical outcome and immunological stress after cardiac surgery

Abstract: Background: Molecular mechanisms underlying perioperative acute phase reactions in cardiac surgery are largely unknown. We aimed to characterise perioperative…

Date: 2024-01-16

Association between hyponatremia and adverse clinical outcomes of heart failure: current evidence based on a systematic review and meta-analysis

Abstract: Background: Heart failure (HF) is a global health challenge. The perturbations in fluid and electrolyte equilibrium, particularly the compromised sodium balance…

Date: 2024-01-16

Causal association of immune cells and polycystic ovarian syndrome: a Mendelian randomization study

Abstract: Background: Polycystic ovarian syndrome (PCOS) is a common reproductive disorder that affects a considerable number of women worldwide. It is accompanied by irregular…

Date: 2024-01-16