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Effects of menopausal hormone therapy on gut microbiota in postmenopausal women and the relationship with bone metabolism

Abstract: Menopausal Hormone Replacement Therapy (MHT) is widely used by peri- and post-menopausal women to alleviate menopause-related symptoms and preventing bone loss, but the…

Date: 2025-10-27

Analysis of risk factors and development of a prediction model for long-term prognosis in patients with ischemic heart failure after percutaneous coronary intervention

Abstract: This study aimed to investigate the factors influencing the long-term prognosis of patients with ischemic heart failure (IHF) after percutaneous coronary intervention…

Date: 2025-10-27

Differential expression of platelet CD147 in moderate altitude conditions: implications for coronary plaque stability assessment

Abstract: As a major contributor to global death rates, coronary heart disease (CHD) remains critical. This investigation examines CD147's utility for assessing plaque…

Date: 2025-10-27

Establishment of prognostic signature based on neutrophil extracellular traps-related genes in acute myeloid leukemia: a bioinformatics analysis

Abstract: Acute myeloid leukemia (AML) is a hematological malignancy with a high incidence of febrile neutropenia during the first two treatment cycles. This study aims to develop…

Date: 2025-10-24

Sleep quality during preparation for RAI: recombinant TSH vs. levothyroxine withdrawal

Abstract: Patients with differentiated thyroid cancer (DTC) suffer from impaired sleep quality, which may be further impaired after radioactive iodine (RAI) treatment. The…

Date: 2025-10-24

Interplay of endocrine and psychological factors in IVF/ICSI outcomes: a prospective cohort analysis

Abstract: Infertility poses considerable challenges to both the endocrine system and psychological well-being of affected women. In particular, those undergoing Assisted…

Date: 2025-10-24

Single-cell RNA sequencing analysis reveals the critical role of fibroblasts in aortic progeria-associated vascular remodeling in Hutchinson-Gilford progeria syndrome mice

Abstract: Patients with Hutchinson-Gilford progeria syndrome (HGPS) typically succumb to cardiovascular diseases in their teens. Although fibroblasts have been implicated in the…

Date: 2025-10-24

Comparative real-world effectiveness and safety of biologics and JAK inhibitors in atopic dermatitis: short- and medium-to-long-term analysis from a regional healthcare network in southern Spain

Abstract: Biologics and Janus kinase (JAK) inhibitors have expanded treatment options for moderate-to-severe atopic dermatitis (AD), but comparative real-world data remain…

Date: 2025-10-24

Allergy diagnostic performance of FastCheckPOC 20 Atopy

Abstract: The increasing prevalence of allergic diseases, along with their diagnosis and treatment, presents a growing challenge in health care. To reduce this burden, a highly…

Date: 2025-10-24

Screened prevalence of trichotillomania and its association with self-esteem among Saudi medical students: a cross-sectional study

Abstract: Trichotillomania is a chronic psychiatric syndrome characterized by an uncontrollable urge to pull out one’s hair. The current diagnostic criteria for Trichotillomania…

Date: 2025-10-24