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Predictors of early morbidity and mortality in newly diagnosed multiple myeloma: data from five randomized, controlled, phase III trials in 3700 patients

Abstract: Early morbidity and mortality affect patient outcomes in multiple myeloma. Thus, we dissected the incidence and causes of morbidity/mortality during induction therapy…

Date: 2023-12-07

Solitary atrial Rhabdomyoma in an infant with tuberous sclerosis: a case report and review of the literature

Abstract: Despite its rare incidence of 1/40,000, fetal cardiac rhabdomyoma (CR) represents the prevailing type of benign cardiac fetal tumors, which commonly affects the…

Date: 2023-12-07

Implications of Sex Differences on the Treatment Effectiveness in Heart Failure with Reduced Ejection Fraction Related to Clinical Endpoints and Quality of Life

Abstract: This narrative review will emphasize the necessity for more female enrollment in heart failure (HF) trials and proposes future investigations regarding optimal dosages.…

Date: 2023-12-07

Concomitant use of monoamine oxidase inhibitor and tyrosine in parenteral nutrition

Abstract: Monoamine oxidase inhibitors (MAOIs) prevent the breakdown of tyramine in the body, and can cause a sudden increase in blood pressure with significant tyramine build up.…

Date: 2023-12-07

Bosutinib: Pediatric First Approval

Abstract: Bosutinib (BOSULIF®), an orally administered BCR–ABL tyrosine kinase inhibitor (TKI) developed by Pfizer Inc., is well established in the EU and the USA as a treatment…

Date: 2023-12-07

Preoperative dental screening can reduce periprosthetic infections of hip and knee endoprostheses in the first month after surgery: results of a cohort study

Abstract: The oral cavity and, in particular, potential oral foci might pose a risk of periprosthetic joint infection (PJI). The aim of this cohort study was to determine whether…

Date: 2023-12-07

Eight-year chronic wound caused by Tarlov’s cyst: a case report

Abstract: Tarlov’s cyst is often underdiagnosed since it is difficult to identify without imaging assistance. Herein, we report the case of a young girl who presented with an…

Date: 2023-12-07

Development of osteonecrosis and improved survival in B-ALL: results of Children’s Oncology Group Trial AALL0232

Abstract: Osteonecrosis is a significant toxicity of acute lymphoblastic leukemia (ALL) therapy. In retrospective analyses, superior event-free survival was noted among affected…

Date: 2023-12-07

The Role of Rehabilitation in Neurological Critical Care: Innovations in Early Mobilization

Abstract: This review appraises the existing literature to highlight the benefits, barriers, and role of rehabilitation in the early mobilization of patients in neurological…

Date: 2023-12-07

Sulcus Tube Internal Needle Guidewire Technique for Glaucoma Drainage Device Placement: Improving Surgical Ease and Precision

Abstract: Despite the rise of micro-invasive glaucoma surgery (MIGS), glaucoma drainage device implantation continues to be a mainstay among glaucoma surgical treatment options.…

Date: 2023-12-07