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IL-33/ST2L signaling alleviates diabetic nephropathy by regulating endoplasmic reticulum stress and apoptosis

Abstract: Diabetic nephropathy (DN) is a serious chronic complication of diabetes mellitus (DM). Endoplasmic reticulum (ER) stress is an important factor in the regulation of…

Date: 2023-12-05

Factors influencing poor response to type 2 targeted therapies in severe asthma: a retrospective cohort study

Abstract: A significant breakthrough has been made in treating severe asthma, with the recognition of various asthma phenotypes and an updated management guideline. Type 2…

Date: 2023-12-05

Development and validation of two nomograms for predicting overall survival and Cancer-specific survival in prostate cancer patients with bone metastases: a population-based study

Abstract: Prostate cancer with bone metastasis has significant invasiveness and markedly poorer prognosis. The purpose of this study is to establish two nomograms for predicting…

Date: 2023-12-05

Treatment of brainstem and fourth ventricle lesions by the full neuroendoscopic telovelar approach

Abstract: To explore the surgical techniques, advantages, and disadvantages of neuroendoscopic telovelar approach in the treatment of brainstem and fourth ventricle lesions.

Date: 2023-12-05

Antioxidant and antidiabetic flavonoids from the leaves of Dypsis pembana (H.E.Moore) Beentje & J.Dransf., Arecaceae: in vitro and molecular docking studies

Abstract: Oxidative stress and diabetes are medical conditions that have a growing prevalence worldwide, significantly impacting our bodies. Thus, it is essential to develop new…

Date: 2023-12-05

The application of Foley catheter traction technique in extraperitoneal robot-assisted radical prostatectomy

Abstract: To describe a technique to improve exposure of prostate during extraperitoneal robot-assisted radical prostatectomy (EP-RARP).

Date: 2023-12-05

Clinical and Pathologic Predictors of Tumor Deposits in Colorectal Cancer

Abstract: Tumor deposits (TDs) are a special metastatic pattern of colorectal cancer (CRC). This study aims to explore the pathological characteristics of TD and find out the risk…

Date: 2023-12-05

A global systematic evidence review with meta-analysis of the epidemiological characteristics of the 2022 Mpox outbreaks

Abstract: In 2022, there were outbreaks of Mpox where the disease is not endemic. We summarized published full-text epidemiological data from the outbreaks.

Date: 2023-12-05

Resident Assessment of Clinician Educators According to Core ACGME Competencies

Abstract: The Accreditation Council for Graduate Medical Education (ACGME) requires faculty to pursue annual development to enhance their teaching skills. Few studies exist on how…

Date: 2023-12-05

Geraniol reverses obesity by improving conversion of WAT to BAT in high fat diet induced obese rats by inhibiting HMGCoA reductase

Abstract: Present report evaluates the protective effect of geraniol on high fat diet (HFD) induced obesity in rats and also determines the molecular mechanism of it.

Date: 2023-12-05