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Cordymin alleviates osteoporosis induced by hindlimb unloading via regulating the gut - microelements -bone axis --for non-clinical studies

Abstract: The purpose of this study was to evaluate the protective effects of cordymin on osteoporosis induced by hindlimb unloading(HLU) in rats and whether cordymin can prevent…

Date: 2023-12-01

Characteristics of neonatal hypoxic-ischemic encephalopathy at high altitude and early results of therapeutic hypothermia

Abstract: Altitude hypoxia and limited socioeconomic conditions may result in distinctive features of neonatal hypoxic-ischemic encephalopathy (HIE). Therapeutic hypothermia (TH)…

Date: 2023-12-01

Colon-targeted S100A8/A9-specific peptide systems ameliorate colitis and colitis-associated colorectal cancer in mouse models

Abstract: The link between chronic inflammation and cancer development is well acknowledged. Inflammatory bowel disease including ulcerative colitis and Crohn’s disease frequently…

Date: 2023-12-01

Voltage-gated potassium channels control extended access cocaine seeking: a role for nucleus accumbens astrocytes

Abstract: Dopaminergic signaling in the nucleus accumbens shell (NAc) regulates neuronal activity relevant to reward-related learning, including cocaine-associated behaviors.…

Date: 2023-12-01

MARCKS regulates tonic and chronic active B cell receptor signaling

Abstract: Tonic or chronic active B-cell receptor (BCR) signaling is essential for the survival of normal or some malignant B cells, respectively. However, the molecular mechanism…

Date: 2023-12-01

Quercetin is a Potential Therapy for Rheumatoid Arthritis via Targeting Caspase- Through Ferroptosis and Pyroptosis

Abstract: Rheumatoid arthritis is a chronic inflammatory autoimmune disease characterized by persistent synovitis and can destroy bone and cartilage tissue, leading to joint…

Date: 2023-12-01

Short-Term Benefits of Smoking Cessation Improve Respiratory Function and Metabolism in Smokers

Abstract: Refrain from smoking is the main therapeutic intervention effective in curbing and reducing the patient’s respiratory functional decline. It is reported in the COPD…

Date: 2023-12-01