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Post-discharge use of opioids, psychostimulants, and treatment medications following residential opioid discontinuation with NET Device™ monotherapy

Abstract: Medical devices offer an established therapeutic approach for managing the transition from polysubstance use to abstinence, but little is known about longer-term…

Date: 2025-10-15

The economic burden of anxiety and depression in Indonesia: evidence from a cross-sectional web panel survey

Abstract: Mental health conditions are the second leading cause of disability in Indonesia, accounting for 13 percent of total years lived with disability. However, little is…

Date: 2025-10-15

Ultrasonographic assessment of optic nerve sheath diameter on the affected and unaffected sides as a predictor of clinical deterioration at discharge in patients with large hemispheric infarction

Abstract: Progressive cerebral edema worsens prognosis in large hemispheric infarction (LHI). Ultrasonographic optic nerve sheath diameter (ONSD) measurement provides a…

Date: 2025-10-15

The longitudinal mediating effect of life-space mobility on the relationship between nutritional status and cognitive function in community-dwelling older stroke patients

Abstract: This study aims to explore the causal relationship between nutritional status, life-space mobility (LSM), and cognitive function in community-dwelling older stroke…

Date: 2025-10-15

Impacts of tacrolimus and glucocorticoids on peripheral blood T and B lymphocyte subsets in myasthenia gravis

Abstract: This study aimed to investigate the impact of tacrolimus on peripheral T and B lymphocyte subsets in myasthenia gravis (MG) patients compared to glucocorticoid…

Date: 2025-10-15

Stage-specific efficacy of pharmacological interventions on gait impairments in Parkinson’s disease

Abstract: This study aims to clarify the variations and the therapeutic effects of medicine on gait by analyzing the gait characteristics before and after medication in various…

Date: 2025-10-15

Associations of white matter hyperintensity with frailty, sarcopenia, and nutritional risk: an analysis of an acute ischemic stroke patient database

Abstract: White matter hyperintensity (WMH), frailty, sarcopenia, and nutritional risk are prevalent and critical factors in geriatric care. This study aimed to investigate the…

Date: 2025-10-15

Serum creatinine-to-albumin ratio as a prognostic marker for short- and long-term mortality in critically ill stroke patients: a MIMIC-IV study

Abstract: Stroke remains a leading cause of mortality and disability worldwide, with critically ill patients facing particularly poor outcomes. Existing prognostic markers often…

Date: 2025-10-15

The synergistic interaction of vitamin D deficiency and insomnia on dizziness-related handicap in patients with benign paroxysmal positional vertigo

Abstract: While insomnia and vitamin D deficiency are known risk factors for BPPV, their interactive effect on the dizziness-related handicap is unknown. Given that both may…

Date: 2025-10-15

Real-world diagnostic value of integrating oral and ocular dryness testing in suspected Sjögren’s disease

Abstract: Sjögren’s disease is an autoimmune condition requiring a systemic evaluation that integrates serologic, histopathologic, and glandular assessments for diagnosis. Current…

Date: 2025-10-15