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Dectin-1 and dectin-2 drive protection against Sporothrix brasiliensis in experimental sporotrichosis

Abstract: The emerging fungal pathogen Sporothrix brasiliensis has been responsible for epidemic outbursts of sporotrichosis in Latin America, particularly Brazil, in recent…

Date: 2025-09-25

Increased acid sphingomyelinase levels in saliva as oral mucositis severity predictors

Abstract: Radiotherapy (RT) plays a central role in multidisciplinary treatment approaches in cancer therapy, particularly as an effective primary treatment modality for patients…

Date: 2025-09-25

Artificial intelligence–assisted rectus femoris ultrasound vs. L3 computed tomography for sarcopenia assessment in oncology patients: establishing diagnostic cut-offs for muscle mass and quality

Abstract: Sarcopenia is prevalent among oncological patients; its diagnosis remains challenging due to technical limitations. This study aims to compare an AI-assisted ultrasound…

Date: 2025-09-25

Global burden of head and neck cancer: Epidemiological transitions, inequities, and projections to 2050

Abstract: Head and neck cancer (HNC) is the seventh most frequently occurring cancer worldwide. The incidence and mortality of HNC have been demonstrated to significantly impact…

Date: 2025-09-25

Impact of chemotherapy on humoral and cellular immune responses to COVID-19 vaccination in patients with solid tumors

Abstract: Despite SARS-CoV-2 pandemic has subsided, vaccine response profiling in patients with cancer remains critical. We longitudinally assessed humoral and cellular immunity…

Date: 2025-09-25

Terrestrial radiotherapy alters microhardness and surface micromorphology of dental restorative materials: an in vitro study

Abstract: Therapeutic radiotherapy, commonly used in the treatment of head and neck cancers, may alter the mechanical and surface properties of restorative dental materials.…

Date: 2025-09-25

Building and sustaining infection prevention and control teams at two pediatric cancer units in Ecuador and Guatemala through a collaboration partnership

Abstract: Hospital infection prevention and control (IPC) programs are often insufficient to meet the needs of pediatric oncology units (POUs) in low-resource settings.…

Date: 2025-09-25

Determination and clinical features of bone pseudoprogression in metastatic breast cancer

Abstract: Bone is one of the most common sites of metastasis for breast cancer. The classification of new osteoblastic lesions as progressive disease is currently controversial.…

Date: 2025-09-25

Relationship between nontraditional lipid parameters and the risk of type 2 diabetes in individuals recovered from dyslipidemia: a cohort study

Abstract: Lipid profiles are essential for assessing type 2 diabetes (T2D) risk, but individuals who recover from dyslipidemia are often overlooked, leaving their residual risk…

Date: 2025-09-25

Elevated novel inflammatory markers in heart failure patients are associated with increased risk of adverse outcomes within one year: insights from a longitudinal study

Abstract: Inflammation has been widely recognized as a key contributor to the pathogenesis of numerous diseases, including cardiovascular disorders. This study aims to investigate…

Date: 2025-09-25