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What works, how and in which contexts when supporting parents to implement intensive speech and language therapy at home for children with speech sound disorder? A protocol for a realist review

Abstract: Introduction Speech and language therapists (SLTs) worldwide report challenges with providing recommended, evidence-based intervention intensity for children with speech…

Date: 2024-01-06

Methods and measures to evaluate the impact of participatory model building on public policymakers: a scoping review protocol

Abstract: Introduction Public policymakers are increasingly engaged in participatory model building processes, such as group model building. Understanding the impacts of…

Date: 2024-01-06

Does use of GP and specialist services vary across areas and according to individual socioeconomic position? A multilevel analysis using linked data in Australia

Abstract: Objective Timely access to primary care and supporting specialist care relative to need is essential for health equity. However, use of services can vary according to an…

Date: 2024-01-06

Factors that impact on the quality of life of intestinal failure patients treated with home parenteral nutrition: protocol for a multicentre, longitudinal observational study

Abstract: Background Home parenteral nutrition (HPN) refers to the intravenous administration of macronutrients, micronutrients and fluid. The aims of treatment are to increase…

Date: 2024-01-06

Realist synthesis protocol on the effectiveness of a rapid response system in managing mental state deterioration in acute hospital settings

Abstract: Introduction Patient mental state deterioration impacts patient outcomes, staff and increases costs for healthcare organisations. Mental state is broadly defined to…

Date: 2024-01-06

Multicentre external validation of the prognostic model kidney failure risk equation in patients with CKD stages 3 and 4 in Peru: a retrospective cohort study

Abstract: Objectives To externally validate the four-variable kidney failure risk equation (KFRE) in the Peruvian population for predicting kidney failure at 2 and 5 years. Design…

Date: 2024-01-06

Clinical profile and outcomes of paediatric patients with acute seizures: a prospective cohort study at an urban emergency department of a tertiary hospital in Tanzania

Abstract: Objective Children with seizures require immediate and appropriate intervention in the emergency department (ED). This study describes the clinical profile and outcome…

Date: 2024-01-06

Trends in COPD mortality from 1983 to 2018: protocol for a population-based cohort study in Denmark

Abstract: Introduction Chronic obstructive pulmonary disease (COPD) is one of the leading causes of death worldwide, which is partly contributed to the increasing prevalence of…

Date: 2024-01-06

Effects of liposomal bupivacaine in preoperative fascia iliac block on postoperative pain and delirium in elderly patients undergoing hip fracture surgery: a study protocol for a randomised, parallel controlled prospective clinical study

Abstract: Introduction Postoperative delirium (POD) is the most common acute fluctuating mental state change after hip fractures in older adults. Postoperative pain is a Grade A…

Date: 2024-01-06

Integrative Analyses of Pyrimidine Salvage Pathway-Related Genes Revealing the Associations Between UPP and Tumor Microenvironment

Abstract: In non-malignant cells, nucleotide synthesis predominantly depends on the de novo synthesis pathway, which employs amino acids and glucose and is characterized by…

Date: 2024-01-06