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Use of external control arms in immune-mediated inflammatory diseases: a systematic review

Abstract: Objectives External control arms (ECAs) provide useful comparisons in clinical trials when randomised control arms are limited or not feasible. We conducted a systematic…

Date: 2023-12-09

Latin American Cerebral Palsy Register (LATAM-CPR): study protocol to develop a collaborative register with surveillance of children with cerebral palsy in Latin American countries

Abstract: Introduction Cerebral palsy (CP) is one of the leading causes of childhood disability globally with a high burden in low-income and middle-income countries (LMICs).…

Date: 2023-12-09

Qualitative study of COVID-19 patient experiences with non-invasive ventilation and pronation: strategies to enhance treatment adherence

Abstract: Introduction Non-invasive ventilation (NIV) treatment combined with pronation in patients with COVID-19 respiratory failure has been shown to be effective in improving…

Date: 2023-12-09

Roles and experiences of informal caregivers of older adults in community and healthcare system navigation: a scoping review

Abstract: Objective Informal caregivers are playing a vital role in improving the degree to which older adults access community and healthcare systems in a more seamless and…

Date: 2023-12-09

Non-pharmacological interventions in primary care to improve the quality of life of older patients with palliative care needs: a systematic review of randomised controlled trials

Abstract: Objectives Our systematic review aimed to summarise non-pharmacological interventions applicable in primary care that improve the quality of life of older patients with…

Date: 2023-12-09

What do older people who have attempted suicide experience? Study protocol for a qualitative meta-synthesis among older adults, family caregivers and healthcare professionals

Abstract: Introduction Attempted suicide among older adults represents a significant mental health concern that has witnessed a rising incidence within this demographic in recent…

Date: 2023-12-09

ProFertil study protocol for the investigation of gonadotropin-releasing hormone agonists (GnRHa) during chemotherapy aiming at fertility protection of young women and teenagers with cancer in Sweden—a phase III randomised double-blinded placebo-controlled study

Abstract: Background Gonadotropin-releasing hormone agonists (GnRHa) cotreatment used to transiently suppress ovarian function during chemotherapy to prevent ovarian damage and…

Date: 2023-12-09

Key performance indicators in extracorporeal membrane oxygenation (ECMO): protocol for a systematic review

Abstract: Introduction Extracorporeal membrane oxygenation (ECMO) is an intervention used in critically ill patients with severe cardiopulmonary failure that is expensive and…

Date: 2023-12-09

Large language model-based information extraction from free-text radiology reports: a scoping review protocol

Abstract: Introduction Radiological imaging is one of the most frequently performed diagnostic tests worldwide. The free-text contained in radiology reports is currently only…

Date: 2023-12-09

Effects of repetitive transcranial magnetic stimulation over the contralesional dorsal premotor cortex on upper limb function in severe ischaemic stroke: study protocol for a randomised controlled trial

Abstract: Introduction Repetitive transcranial magnetic stimulation (rTMS) is an evidence-based treatment widely recommended to promote hand motor recovery after ischaemic stroke.…

Date: 2023-12-09