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Protocol for the Tallaght University Hospital Institute for Memory and Cognition-Biobank for Research in Ageing and Neurodegeneration

Abstract: Introduction Alzheimer’s disease and other dementias affect >50?million individuals globally and are characterised by broad clinical and biological heterogeneity. Cohort…

Date: 2023-12-09

Methodology and application of three-dimensional technology for brace design and production for treatment in patients with adolescent idiopathic scoliosis: a scoping review protocol

Abstract: Introduction Conservative treatment for adolescent idiopathic scoliosis (AIS) using bracing has proven to be effective at reducing curve progression. However, variation…

Date: 2023-12-09

Effects of the different intensities of task-oriented training on the upper extremity motor function and self-care ability of stroke survivors: study protocol for a multiarm parallel-group randomised controlled trial in a tertiary hospital in China

Abstract: Introduction Although task-oriented training (TOT) may provide added therapeutic value to stroke survivors, current TOT guidance offers insufficient advice on…

Date: 2023-12-09

Differentiating Alzheimer’s disease from mild cognitive impairment: a quick screening tool based on machine learning

Abstract: Background Alzheimer’s disease (AD) is a neurodegenerative disorder characterised by cognitive decline, behavioural and psychological symptoms of dementia (BPSD) and…

Date: 2023-12-09

Investigating trial design variability in trials of disease-modifying therapies in Parkinson’s disease: a scoping review protocol

Abstract: Introduction Parkinson’s disease (PD) is a debilitating neurological disorder for which the identification of disease-modifying interventions represents a major unmet…

Date: 2023-12-09

Prevalence and risk factors of metabolic syndrome in Ethiopia: describing an emerging outbreak in HIV clinics of the sub-Saharan Africa – a cross-sectional study

Abstract: Objectives HIV-induced chronic inflammation, immune activation and combination antiretroviral therapy (cART) are linked with adverse metabolic changes known to cause…

Date: 2023-12-09

Does atrial fibrillation affect prognosis in hospitalised COVID-19 patients? A multicentre historical cohort study in the Netherlands

Abstract: Objectives The aim of this multicentre COVID-PREDICT study (a nationwide observational cohort study that aims to better understand clinical course of COVID-19 and to…

Date: 2023-12-09

Trends in age of tobacco use initiation over time in Bangladesh, India and Pakistan: analysis of cross-sectional nationally representative surveys

Abstract: Objective Tobacco use begins at an early age and typically leads to a long-term addiction. The age of initiation for tobacco use is not well studied in South Asia, where…

Date: 2023-12-09

Risk prediction and treatment assessment in glioma patients using SEER database: a prospective observational study

Abstract: Objectives To use a nomogram to predict the risk of mortality and estimate the impact of current treatment on the prognosis of glioma patients. Methods A total of 3798…

Date: 2023-12-09

Protocol for a prospective cohort study on the feasibility of application of nutritional ultrasound in the diagnosis and follow-up of patients with nutritional risk at hospital discharge: study on body composition and function (DRECO)

Abstract: Introduction Nutritional ultrasound (US) is an emerging technique in clinical nutrition for the morphological and structural study of muscle mass. Currently, all…

Date: 2023-12-09