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Knowledge, beliefs, perceived barriers, and previous upper gastrointestinal endoscopy use regarding Helicobacter pylori and gastric cancer prevention among community residents: a cross-sectional study

Abstract: Low adherence to primary and secondary prevention strategies for gastric cancer remains a major public health challenge. Understanding knowledge, beliefs, perceived…

Date: 2026-08-14

Efgartigimod as a salvage therapy for anti-NMDAR encephalitis patients after first-line treatment failure: a case series

Abstract: As an Fc receptor inhibitor, efgartigimod (EFG) could reduce serum IgG level, which might have a positive effect in the treatment of anti-N-methyl-D-aspartate-receptor…

Date: 2026-08-14

Pre-vaccination biomarkers of enteric dysfunction, inflammation and nutritional status associate with seroconversion to oral cholera vaccine and are perturbed during natural infection

Abstract: Oral cholera vaccines (OCVs) show variable immunogenicity in endemic settings. Host factors including enteric dysfunction, systemic inflammation, and nutritional status…

Date: 2026-08-14

Interpretable machine learning enables early identification of financial risk and resource optimization in colorectal cancer surgery

Abstract: Colorectal cancer (CRC) imposes major clinical and economic pressure on health systems. Under diagnosis-related group (DRG) payment, fixed reimbursement benchmarks may…

Date: 2026-08-14

Two-hour dynamic reassessment of noninvasive ventilation failure risk in acute exacerbation of chronic obstructive pulmonary disease with hypercapnic respiratory failure: development and temporal validation

Abstract: Early recognition of noninvasive ventilation (NIV) failure remains difficult in acute exacerbation of chronic obstructive pulmonary disease (AECOPD) with hypercapnic…

Date: 2026-08-14

Investigation of clinical applicability of deep learning-based virtual contrast-enhanced MRI for nasopharyngeal carcinoma patients

Abstract: There is a lack of research evaluating the clinical performance of virtual contrast-enhanced MRI (VCE-MRI). This study aims to assess the clinical utility of an…

Date: 2026-08-14

Gantry-period-guided modulation factor selection in helical tomotherapy: effects on delivery efficiency, dosimetry and verification accuracy

Abstract: To explore a gantry-period-guided strategy for identifying a lower useful modulation factor (MF) in helical tomotherapy under fixed field width and pitch. Twenty…

Date: 2026-08-14

Metformin modulates the phenotypes of tumor-associated macrophages in glioblastoma in a context-dependent manner by promoting the homeostasis of macrophages

Abstract: Glioblastoma (GBM) remains the most aggressive primary adult brain cancer attributed to its immunosuppressive nature. Radiation therapy (RT) and concurrent temozolomide…

Date: 2026-08-14

Early dynamic immune-inflammatory and nutritional recovery signature is associated with durable benefit and early progression in advanced non-small cell lung cancer receiving first-line PD-1/PD-L1 inhibitor-based therapy: a real-world retrospective cohort study

Abstract: Durable benefit from first-line PD-1/PD-L1 inhibitor-based therapy remains heterogeneous in advanced non-small cell lung cancer (NSCLC). Baseline biomarkers, including…

Date: 2026-08-14

Relation of climatic exposures with intrahepatic cholestasis of pregnancy in a two-center retrospective cohort

Abstract: To investigate relation between climatic exposures and intrahepatic cholestasis of pregnancy (ICP) in Chinese cities Shanghai and Sanya. ICP is a pregnancy-specific…

Date: 2026-08-14