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Prophylactic epidural blood patch for cerebrospinal fluid leakage after intrathecal drug delivery system implantation in patients with refractory cancer pain: a multi-center retrospective cohort study

Abstract: Current guidelines for postdural puncture cerebrospinal fluid (CSF) leakage advocate conservative management, extrapolated from general populations. Patients with…

Date: 2026-07-16

Elevated GDF15 in ocular fluids of patients with proliferative diabetic retinopathy

Abstract: Growth differentiation factor 15 (GDF15) is a multifunctional stress-responsive cytokine widely involved in inflammation, oxidative stress, and microvascular injury. Its…

Date: 2026-07-16

SGLT2 inhibitors and diabetic retinopathy progression: evidence from a retrospective cohort study and Mendelian randomization analysis

Abstract: To investigate the association between sodium-glucose cotransporter 2 inhibitors (SGLT2i) use and diabetic retinopathy (DR) progression, and to explore supporting…

Date: 2026-07-16

Analysis of the effectiveness of arthroscopic cannulated screw fixation for coracoid process fractures

Abstract: To evaluate the effectiveness of minimally invasive arthroscopic treatment for coracoid process fractures. This retrospective study analyzed 17 patients with coracoid…

Date: 2026-07-16

Integrated single-cell and bulk RNA sequencing analyses identify a myeloid state-related gene signature for molecular subtyping in stomach adenocarcinoma

Abstract: Stomach adenocarcinoma (STAD) is characterized by significant heterogeneity, within which myeloid cells play crucial yet incompletely understood roles. The relationship…

Date: 2026-07-16

Infusion-related reactions and premedication patterns in ublituximab-treated multiple sclerosis patients: a multicenter real-world study

Abstract: Ublituximab is a glycoengineered monoclonal antibody that effectively reduces multiple sclerosis (MS) relapses but carries a significant risk of infusion-related…

Date: 2026-07-16

Quantitative assessment of inter-observer consistency in target volume delineation following breast-conserving surgery and mastectomy

Abstract: Consistent clinical target volume (CTV) delineation is vital for breast cancer radiotherapy. While organs-at-risk definitions are increasingly automated, manual CTV…

Date: 2026-07-16

TyG index predicts adverse cardiovascular outcomes in patients with multimorbidity of hypertension and obstructive coronary artery disease: a cohort study

Abstract: Whether elevated triglyceride-glucose (TyG) index is linked to long-term prognosis in individuals with hypertension and obstructive coronary artery disease (OCAD)…

Date: 2026-07-16

The association between the red blood cell distribution width-to-albumin ratio and in-hospital mortality in cardiac arrest patients: an analysis of the eICU database

Abstract: Cardiac arrest triggers systemic ischemia-reperfusion injury, which initiates a cascade of inflammatory responses that particularly damage cerebral and myocardial…

Date: 2026-07-16

The impact of pretransplant consolidation chemotherapy on clinical outcomes in adult patients with Philadelphia chromosome-negative acute lymphoblastic leukemia: a single-center retrospective study

Abstract: Acute lymphoblastic leukemia (ALL) is a malignant hematological disease that accounts for approximately 20% of adult leukemia. Allogeneic hematopoietic stem cell…

Date: 2026-07-15