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Mechanistic insights into lipoprotein(a)-induced cardiomyocyte ferroptosis via ROS/p38/p53 signaling

Abstract: Lipoprotein(a) [Lp(a)], a low-density lipoprotein-like molecule covalently linked to apolipoprotein (a), is a residual cardiovascular risk factor with established…

Date: 2026-07-13

Cumulative triglyceride-glucose-body mass index exposure and cardiovascular disease risk: findings from the Kailuan study

Abstract: The relationship between cumulative triglyceride-glucose-body mass index (TyG-BMI) exposure and the risk of cardiovascular disease (CVD) has been unclear. This study…

Date: 2026-07-13

Integrated multi-omics profiling of the early post-infarct heart reveals a hub gene network associated with myeloid-driven inflammation

Abstract: The early inflammatory phase (EIP, 0–72?h) post-acute myocardial infarction (AMI) is a critical determinant of cardiac repair and clinical outcomes. However, a…

Date: 2026-07-13

Immunomodulatory effects of HUC-MSCs therapy: enhancing adaptive and innate immune responses in aging frailty

Abstract: Frailty associated with aging, characterized by chronic inflammation and immune dysfunction, poses a significant public health challenge. Human umbilical cord-derived…

Date: 2026-07-13

Integrated management of atrial fibrillation and comorbidities in the community: a generalist-specialist collaborative RCT and subgroup analysis

Abstract: To develop, implement, and evaluate a community-based, patient-centered integrated care model for atrial fibrillation (AF) characterized by generalist-specialist…

Date: 2026-07-13

Implementation of evidence-based personalized nursing care for Two patients With vasodepressor syncope: a case report

Abstract: Vasodepressor syncope is a common subtype of reflex syncope. Although lifestyle modification, trigger avoidance, physical counterpressure manoeuvres, and orthostatic…

Date: 2026-07-13

Evaluation of pre-dilution combined with optical/fluorescent platelet counting for correcting pseudothrombocytopenia

Abstract: Pseudothrombocytopenia (PTCP), a common artifact in hematology, often leads to misdiagnosis and unnecessary interventions, with EDTA-dependent PTCP being the most…

Date: 2026-07-10

Hemodynamic effects of finerenone on blood pressure and heart rate in hospitalized patients with type 2 diabetes: a real-world study

Abstract: While the long-term cardiorenal benefits of finerenone have been established in landmark clinical trials, its immediate impact on hemodynamic parameters in routine…

Date: 2026-07-10

Individualized osilodrostat treatment for patients with ACTH-dependent Cushing’s syndrome: real-world evidence

Abstract: Osilodrostat is an 11?-hydroxylase inhibitor that has demonstrated high efficacy in Cushing’s syndrome (CS) in clinical trials; however, real-world data remain limited.…

Date: 2026-07-10

Value of thyroid volume as a complementary indicator for initial levothyroxine dosing in congenital hypothyroidism: a retrospective cohort study

Abstract: This study aimed to generate hypotheses on the effectiveness and safety of pre-treatment thyroid volume as an adjunctive parameter for guiding initial levothyroxine…

Date: 2026-07-10