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Serum and serum-derived extracellular vesicle microRNA signatures linked to neurodevelopmental processes in central precocious puberty

Abstract: Central precocious puberty (CPP) results from premature activation of the hypothalamic–pituitary–gonadal (HPG) axis. While hormonal mechanisms underlying pubertal…

Date: 2026-07-10

Clinical characteristics and macrolide resistance analysis of pertussis in children: a retrospective study

Abstract: Pertussis is mainly caused by Bordetella pertussis . Currently, no reports exist on the incidence of B. pertussis infection or on its patterns of macrolide resistance…

Date: 2026-07-10

Factors associated with unmet psychological care needs and development of a Neuman systems model-based risk prediction model in patients with hepatocellular carcinoma

Abstract: Patients with hepatocellular carcinoma (HCC) often face symptom distress, treatment decision-making, demands for family support, communication needs, and financial…

Date: 2026-07-10

Clinical efficacy of manual reverse closed reduction and robot-assisted cannulated screw fixation for valgus-impacted osteoporotic femoral neck fractures in the elderly: a retrospective cohort study

Abstract: Achieving anatomical restoration in valgus-impacted femoral neck fractures remains a clinical challenge, particularly in the elderly. This retrospective study evaluated…

Date: 2026-07-10

Development and validation of a clinical prediction model for postcontrast acute kidney injury in patients with postoperative acute kidney injury of acute Stanford type A aortic dissection

Abstract: To identify independent risk factors for postcontrast acute kidney injury (PC-AKI) in patients with postoperative AKI (PO-AKI) following acute Stanford type A aortic…

Date: 2026-07-10

Effects and mechanisms of lifespan extension and healthspan promotion induced by Limosilactobacillus reuteri ( Lactobacillus reuteri ) A21041

Abstract: Nowadays probiotics have been widely used in the fields of food, medicine and agriculture. In this study, we investigated the anti-aging effects of the probiotic strain…

Date: 2026-07-10

Clinical characteristics and cytokine profiles for early prediction of severe Mycoplasma pneumoniae pneumonia in children: a prospective cohort study

Abstract: To investigate the clinical characteristics and cytokine profiles of children with Mycoplasma pneumoniae pneumonia (MPP) and to establish a predictive nomogram for the…

Date: 2026-07-10

Association between laboratory-based frailty index and unfavorable treatment outcomes in older adults with drug-susceptible pulmonary tuberculosis in the Republic of Korea: a retrospective cohort study

Abstract: Older adults with drug-susceptible pulmonary tuberculosis (DS-PTB) face disproportionately poor treatment outcomes, but practical tools for risk stratification around…

Date: 2026-07-10

Immune-inflammatory and metabolic signatures for osteoporosis risk stratification in primary Sjögren’s syndrome: development and internal validation of an interpretable machine-learning model

Abstract: Primary Sjögren’s syndrome (pSS) is a systemic autoimmune disease. Osteoporosis (OP) is a common complication in patients with pSS (pSS-OP), which significantly affects…

Date: 2026-07-10

Evaluation of the Saudi Healthy Eating Index

Abstract: The Saudi Healthy Eating Index (SHEI) was developed to evaluate adherence to the Saudi Healthy Plate Guide 2024. This study aimed to conduct a preliminary assessment of…

Date: 2026-07-10