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Keratinocyte-derived CXCL-CXCR2 ligand-receptor axis by MED1 orchestrates neutrophil phenotypes during psoriasis

Abstract: Psoriasis is a chronic inflammatory skin disease characterized by aberrant keratinocyte proliferation and dysregulated immune responses. Increasing evidence suggests…

Date: 2026-09-30

Immunogenic cell death and tertiary lymphoid structures jointly define dysregulated antitumor immune states and therapeutic vulnerability in lung adenocarcinoma

Abstract: Immunogenic cell death (ICD) and tertiary lymphoid structures (TLSs) are biologically distinct yet interconnected components of antitumor immunity. ICD promotes…

Date: 2026-09-30

Oxaliplatin desensitization for gastrointestinal cancer patients with hypersensitivity reactions: real-world experience from Vietnam

Abstract: Oxaliplatin-induced hypersensitivity reactions (HSRs) can interrupt clinically indicated treatment for gastrointestinal malignancies. We evaluated the early…

Date: 2026-09-30

Local control after stereotactic radiation for thyroid cancer: a histology risk-stratified analysis

Abstract: Recurrent and metastatic non-anaplastic thyroid cancer has traditionally been considered relatively radioresistant. We evaluated whether anatomic site or histology risk…

Date: 2026-09-30

Uncovering the mortality burden of lung cancer with documented sleep apnea in the United States: a 22-year population-based study

Abstract: Lung cancer remains the leading cause of cancer-related mortality worldwide, and sleep apnea may identify a clinically vulnerable subgroup of patients with lung cancer.…

Date: 2026-09-30

A peri-tumoral TREM2-high myeloid state, myeloid continuum polarization, and white matter disconnection in long-term cognitive survivorship after diffuse glioma: a neuroimmune-connectomic cohort study

Abstract: Whether a TREM2-high myeloid state and myeloid continuum polarization are associated with long-term cognitive survivorship in diffuse glioma has not been integrated with…

Date: 2026-09-30

Efficacy and safety of bevacizumab plus XELOX in patients with unresectable locally advanced or metastatic neuroendocrine tumors

Abstract: Neuroendocrine tumors (NETs) are highly vascularized malignancies for which effective treatment options remain limited in the unresectable locally advanced or metastatic…

Date: 2026-09-30

Preoperative biopsy underestimates tumour budding but retains prognostic value in oral squamous cell carcinoma

Abstract: Tumour budding is an established prognostic marker in oral squamous cell carcinoma (OSCC), but its reliability and prognostic performance in preoperative biopsy…

Date: 2026-09-30

Implementation and feasibility of DPYD-guided fluoropyrimidine use in a gastrointestinal oncology clinic at an academic medical center

Abstract: Genetic variation in DPYD can result in reduced fluoropyrimidine (FP) metabolism and increased risk of severe toxicity. This DPYD test implementation pilot aimed to…

Date: 2026-09-30

Beyond detection: developing probabilistic hemodynamic phenotyping after a positive point-of-care pulmonary hypertension test

Abstract: Pulmonary hypertension (PH) is a heterogeneous condition in which hemodynamic subtype directs management and specialist referral. PH can be identified non-invasively at…

Date: 2026-09-30