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Histopathological biomarkers of immunotherapy outcome in advanced colorectal cancer: a multicentre retrospective study

Abstract: Immune checkpoint inhibitors (ICIs) have transformed the treatment of advanced colorectal cancer (aCRC), but clinical benefit remains largely confined to patients with…

Date: 2026-07-06

Machine learning for chemotherapy decision-making in breast cancer using large language model

Abstract: Breast cancer chemotherapy decision-making remains challenging due to biological heterogeneity and variability in clinical practice. This study proposes a hybrid…

Date: 2026-07-06

Prognostic significance of the advanced lung cancer inflammation index for long-term mortality in patients with acute myocardial infarction and diabetes

Abstract: The advanced Lung Cancer Inflammation Index (ALI) is a novel composite marker integrating nutritional, metabolic, and inflammatory status. This study aimed to…

Date: 2026-07-06

Effectiveness of structured nursing interventions in reducing complication related morbidity in leukemia patients undergoing hematopoietic stem cell transplantation

Abstract: Hematopoietic stem cell transplantation (HSCT) is a potentially curative treatment for leukemia but is associated with high rates of complication-related morbidity,…

Date: 2026-07-03

Physicians’ attitudes and perceptions toward the integration of artificial intelligence into pediatric hematology–oncology in Saudi Arabia

Abstract: With increasing interest in integrating artificialPrevalence of nasal myiasis in slaughtered camels intelligence (AI) into healthcare in Saudi Arabia, many benefits of…

Date: 2026-07-03

Upregulated CD177 on neutrophils is implicated in sepsis pathogenesis and necroptosis-driven inflammation

Abstract: Sepsis remains a leading cause of mortality in critical care, with dysregulated inflammatory responses driving disease progression. However, the role of necroptosis in…

Date: 2026-07-03

Evolution of clinical benefit in cancer trials: comparing pivotal approval data with updated efficacy

Abstract: Many oncology drugs are approved by the Food and Drug Administration (FDA) based on interim analyses from randomized controlled trials (RCTs) using immature efficacy…

Date: 2026-07-03

Association of the new TyG indicator–TyHGB with prediabetes and diabetes in middle-aged and elderly postmenopausal women: a longitudinal study

Abstract: Given the established relationship between lipid metabolism and dysglycemia, this longitudinal study aimed to investigate the association between the triglyceride-high…

Date: 2026-07-03

Sex and gender-oriented colorectal cancer screening: a consensus study from the AIOM- GISEG working group

Abstract: Gender medicine in oncology focuses on understanding the differences in cancer incidence, progression and responses to oncological treatments between men and women.…

Date: 2026-07-03

Clinical and immunomicrobiome correlates of a standardized Qingpao Chushi Jiedu Fang regimen in palmoplantar pustulosis

Abstract: Palmoplantar pustulosis (PPP) is a chronic inflammatory dermatosis with limited therapeutic options. Traditional Chinese Medicine (TCM) formulations may benefit PPP, yet…

Date: 2026-07-03