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Characterization of novel arrhythmogenic patterns arising secondary to heterogeneous expression and activation of Nav1.8

Abstract: Background: Previous studies suggested that SCN10A/Nav1.8 may influence cardiac electrophysiology and the susceptibility to cardiac arrhythmias. Notably, the expression…

Date: 2025-03-20

Food allergen introduction practices and parent/caregiver attitudes based on family history of food allergy

Abstract: Background: The National Institute of Allergy and Infectious Disease (NIAID) addendum guidelines for primary prevention of peanut allergy1 provide recommendations…

Date: 2025-03-19

Is a rare CXCL8 gene variant a new possible cause or curse factor of inflammatory bowel disease?

Abstract: Introduction: The pathogenesis of inflammatory bowel diseases (IBD) involves genetic, environmental, immunological, and microbial factors; however, it remains unclear.…

Date: 2025-03-19

Celecoxib prevents malignant progression of smoking-induced lung tumors via suppression of the COX-2/PGE2 signaling pathway in mice

Abstract: Introduction: Lung cancer is characterized by a poor prognosis and is a significant comorbidity of chronic obstructive pulmonary disease (COPD). Therefore, effective…

Date: 2025-03-19

Adherence to the Mediterranean diet is associated with lower cancer-related fatigue: a cross-sectional analysis from NHANES 2017–2020

Abstract: Background and objectives: Cancer-related fatigue is a common and distressing symptom experienced by cancer patients, which may persist from the time of diagnosis to the…

Date: 2025-03-19

Construction of a predictive model for the efficacy of anti-VEGF therapy in macular edema patients based on OCT imaging: a retrospective study

Abstract: Background: Macular edema (ME) is an ophthalmic disease that poses a serious threat to human vision. Anti-vascular endothelial growth factor (anti-VEGF) therapy has…

Date: 2025-03-19

The strong correlation between visual function improvement and retinal microcirculation enhancement in glaucoma

Abstract: Introduction: This study aimed to investigate the alterations in retinal vessel density (VD) among glaucomatous patients following effective intraocular pressure (IOP)…

Date: 2025-03-19

The association between lipid accumulation product and osteoporosis in American adults: analysis from NHANES dataset

Abstract: Background: The Lipid Accumulation Product (LAP), a novel indicator of fat accumulation, reflects the distribution and metabolic status of body fat. This study aims to…

Date: 2025-03-19

Comprehensive analysis of the ischemic stroke burden at global, regional, and national levels (1990–2021): trends, influencing factors, and future projections

Abstract: Background and purpose: Estimating the global burden of ischemic strokes (IS) is crucial for enhancing prevention and control strategies.

Date: 2025-03-19