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Antidepressants and hypertensive disorders in pregnancy: a retrospective cohort analysis

Abstract: This retrospective cohort study investigated relationships between antidepressant use in pregnancy and hypertensive disorders of pregnancy. Observational cohort study…

Date: 2025-11-27

Study on the correlation between serum total cholesterol levels and suicidal ideation in patients with first-episode drug-naïve schizophrenia: a cross-sectional study

Abstract: The pathological physiology of schizophrenia (SZ) is associated with defects in biological energy metabolism. Abnormal blood lipid levels may influence the emergence of…

Date: 2025-11-27

OXTR rs2254298 polymorphism influences escitalopram response in Generalized Anxiety Disorder: a sex-specific role for oxytocin signaling

Abstract: This study aimed to investigate whether the functional OXTR rs2254298 polymorphism moderates escitalopram response in Generalized Anxiety Disorder (GAD) through oxytocin…

Date: 2025-11-27

The emotion regulation motive of nonsuicidal self-injury mediates the relationship between motor impulsivity and NSSI frequency in adolescents

Abstract: Nonsuicidal self-injury (NSSI) is a common and acute mental health issue among hospitalised adolescents. Although prior research has highlighted the roles of both…

Date: 2025-11-27

Insomnia and depression in Chinese academic researchers: mediation by anxiety and resilience with differences among researchers by educational level

Abstract: Mental health issues such as insomnia may exhibit unique interaction patterns among high-stress populations, with educational attainment potentially playing a…

Date: 2025-11-27

Telemedicine in polish primary care during and after the COVID-19 crisis: a retrospective analysis of over 720,000 consultations

Abstract: The COVID-19 pandemic fundamentally reshaped healthcare delivery worldwide, accelerating the adoption of telemedicine. This study aimed to examine patterns of…

Date: 2025-11-27

The Family Stress Model in families of children with rare diseases: a cross-sectional multilevel path analysis for understanding family dynamics

Abstract: Theoretical frameworks, such as the Family Stress Model, have been evaluated in various contexts; however, there is a lack of large-scale studies specifically focusing…

Date: 2025-11-27

Improving adolescents’ knowledge about mental health and depression: a randomized experimental study of web-based information

Abstract: Adolescents often lack adequate knowledge about mental health and available professional support, which hinders timely help-seeking. As many adolescents seek information…

Date: 2025-11-27

The ENTER study (E-DetectioN Tool for Emerging Mental DisoRders): general population recruitment and data integrity in online screening for psychosis risk

Abstract: Effective detection of young people at clinical high-risk for psychosis (CHR-P) is one of the rate-limiting steps in improving outcomes through preventive treatment.…

Date: 2025-11-27

Transcriptomic profiling of diabetic retinopathy: insights into RPL11 and bisphenol A

Abstract: Diabetic retinopathy (DR) is a leading microvascular complication of diabetes mellitus, causing irreversible vision loss in adults worldwide. However, the molecular…

Date: 2025-11-27