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A case report of TBL1XR1-RARB positive pediatric acute promyelocytic leukemia and literature review

Abstract: Acute promyelocytic leukemia (APL) is classically driven by the PML-RARA fusion oncogene and characterized by a maturation arrest of myeloid precursors. Variant APL…

Date: 2025-08-29

Digital biomarkers as predictors of brain injury in neonatal encephalopathy

Abstract: Neonatal encephalopathy (NE) is a significant cause of neurodevelopmental impairment, with therapeutic hypothermia (TH) being the current standard of care for mitigating…

Date: 2025-08-29

Dynamically grading cerebral collateral circulation using 3D multi-inversion time arterial spin labeling in ischemic stroke: a comparison with digital subtraction angiography

Abstract: This study aims to introduce a novel non-invasive imaging method, 3D multi-inversion time arterial spin labeling (3D mTI-ASL), for grading collateral circulation in…

Date: 2025-08-29

Visualized clinical–radiomics model for predicting the efficacy of surufatinib in hepatic metastases of neuroendocrine neoplasms

Abstract: Hepatic metastatic neuroendocrine neoplasms (HM-NENs) have few treatment biomarkers and low survival rates. We created a clinical–radiomics fusion model to predict…

Date: 2025-08-29

Development and validation of clinical prediction models for cardiorespiratory fitness in atrial fibrillation patients following radiofrequency catheter ablation

Abstract: Assessment of cardiorespiratory fitness (CRF) is imperative in patients with atrial fibrillation (AF) who have had radiofrequency catheter ablation (RFCA). This study…

Date: 2025-08-29

State machine design for an automated peritoneal dialysis machine

Abstract: According to the National Library of Medicine (NLM), chronic kidney disease (CKD) affects more than 10% of the world's population, and peritoneal dialysis (PD) is one of…

Date: 2025-08-29

Triglyceride-glucose index, renal function, sleep duration, and myocardial infarction: a UK biobank cohort study

Abstract: Myocardial infarction (MI) remains a leading cause of cardiovascular morbidity and mortality globally. Insulin resistance, renal function, and sleep duration are key…

Date: 2025-08-29

Development of a novel prognostic score for 1-year survival in immunotherapy-treated patients with unresectable HCC: the ALIVE-IO score

Abstract: There is a lack in reliable and widely used prognostic scores to predict survival in patients with hepatocellular carcinoma (HCC) receiving immunotherapy. The aim of our…

Date: 2025-08-29

Evidence-based veterinary medicine perception by swine veterinarians: a European survey across diverse practitioner profiles

Abstract: Evidence-Based Veterinary Medicine (EBVM) enhances the quality of care by guiding clinical decisions with robust scientific data, leading to more effective disease…

Date: 2025-08-29

Development and validation of nomogram for predicting cognitive frailty with multimorbidity: a cross-sectional study

Abstract: This study aims to develop and validate a nomogram for cognitive frailty in older patients with multimorbidity. From April 2022 to December 1, 2024, a total of 711 older…

Date: 2025-08-29