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Risk factors and impact on outcomes of high-density shadow on immediate cerebral CT after successful interventional recanalization in acute ischemic stroke with large vessel occlusion

Abstract: To explore the risk factors, classification, relation with hemorrhage and clinical significance of high-density shadow on immediate cerebral CT in patients with large…

Date: 2025-11-27

No impact of intravenous thrombolysis on post thrombectomy transcranial Doppler pulsatility index

Abstract: While transcranial Doppler (TCD) studies are beneficial in evaluating macrovascular recanalization post mechanical thrombectomy (MT), they may have a role in estimating…

Date: 2025-11-27

Delayed-onset parkinsonism is common after isolated striatal infarcts

Abstract: While case studies have suggested that only a minority of patients with putaminal lesions develop parkinsonism, existing data are limited by involvement of adjacent…

Date: 2025-11-27

The impact of frailty on cognitive outcomes in elderly patients with post-stroke subjective cognitive complaints

Abstract: Frailty delineates a state of poor health characterized by the accumulation of age-related health deficits, and was associated with cognitive decline in patients with…

Date: 2025-11-27

Levodopa/carbidopa/entacapone versus levodopa/benserazide plus pramipexole in Chinese patients with Parkinson’s disease experiencing wearing off

Abstract: To compare the efficacy and safety of direct switch from levodopa/benserazide (LB) to levodopa/carbidopa/entacapone (LCE) versus LB plus pramipexole (PPX) in Chinese…

Date: 2025-11-27

Self-perceptions of aging and sarcopenia in older adults: the mediating role of IADL

Abstract: Sarcopenia, marked by declines in muscle mass and function, poses a major risk to healthy aging. Self-perceptions of aging (SPA) reflect individuals’ attitudes toward…

Date: 2025-11-27

Correlation study between serum uric acid level and cognitive impairment in middle-aged and elderly patients with hypertension: based on an explainable predictive model

Abstract: Patients with primary hypertension are always comorbid with hyperuricemia. Serum uric acid exhibits a dual role in cognitive function. Evidence regarding the…

Date: 2025-11-27

Cortical morphometric similarity patterns and molecular signatures across ischemic stroke recovery

Abstract: Ischemic stroke is associated with widespread and dynamic brain structural alterations, but the relationship between these changes and underlying molecular signatures…

Date: 2025-11-27

Multiple mediators of anxiety and depression between living space and cognitive function among elderly patients with ischemic stroke

Abstract: To explore the relationship between living space, cognitive function, anxiety, and depression in ischemic stroke patients, specifically examining the mediating roles of…

Date: 2025-11-27

Single-cell transcriptomics identifies FOSL1-regulated IGFBP3+ melanoma subtype as a neuro-immunoregulatory signaling hub facilitating tumor progression

Abstract: The most aggressive type of skin cancer, melanoma, has a high prevalence of metastases and a poor prognosis. Despite advancements in treatment, drug resistance and tumor…

Date: 2025-11-27