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Public perceptions and emotional trends of psychotherapy: a 15-year analysis across English and Spanish language communities on X (twitter)

Abstract: Mental health disorders have been rising globally, and social media platforms provide a unique opportunity to examine public perceptions of psychotherapy. However,…

Date: 2025-12-16

Factors influencing patient decision-making on a multimodal precision medicine algorithm for depression: a qualitative European multicentre study of the PROMPT consortium

Abstract: Precision medicine promises to improve treatment outcomes by tailoring interventions to patients’ individual characteristics. However, the use of precision medicine…

Date: 2025-12-16

Medical-nursing integrated service model in ophthalmic outpatient care for intravitreal injections: a retrospective cohort study

Abstract: Outpatient intravitreal injections are widely utilized in contemporary ophthalmology practice. However, fragmented medical-nursing coordination and compressed clinical…

Date: 2025-12-16

IL-18 receptor axis in allergic conjunctivitis: a multi-omics study

Abstract: The pathophysiology of allergic conjunctivitis (AC) is not fully explained by the traditional Th2-centric model. This study aimed to identify AC-associated candidate…

Date: 2025-12-16

Utility of the non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio in individuals with retinal vein occlusion

Abstract: The ratio of non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol (NHHR) has recently been identified as a novel lipid marker for assessing…

Date: 2025-12-16

Clinical and economic evaluation of robotic vs. freehand screw fixation in femoral neck fractures: advancing precision alignment in orthopedics

Abstract: Femoral neck fractures are common and technically challenging injuries that often require internal fixation, with outcomes influenced by surgeon experience. This study…

Date: 2025-12-16

Metabolomic analysis of synovial fluid from healthy and pathological equine joints and tendon sheaths using high-resolution 1 H Nuclear Magnetic Resonance

Abstract: Joint and tendon sheath diseases are a major cause of lameness and reduced performance in horses. Synovial fluid composition changes in response to pathological…

Date: 2025-12-16

Individual components and cumulative burden of metabolic syndrome are associated with higher disease activity and adverse outcomes in Crohn’s disease

Abstract: The impact of metabolic syndrome (MetS) and its components on Crohn’s disease (CD) remains unclear. This study investigated how individual MetS factors and cumulative…

Date: 2025-12-16

Impact of stress hyperglycemia mediating tissue-level collaterals on futile recanalization in large vessel occlusion patients

Abstract: The stress hyperglycemia ratio (SHR) is associated with unfavorable functional outcomes in patients with large vessel occlusion. The potential effect of SHR on…

Date: 2025-12-16

Isolation of a nanobody specific to the PstS-1 protein and evaluation of its immunoreactivity with structural components of Mycobacterium tuberculosis granuloma

Abstract: Mycobacterium tuberculosis (Mtb) causes infectious granulomatous disease tuberculosis (TB), and existing in vitro TB-diagnosis is insensitive for extrapulmonary TB…

Date: 2025-12-16