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Research Articles Search

Showing 340 of 147,163 result(s)
Yiai Fuzheng decoction inhibits triple-negative breast cancer by remodeling the immune microenvironment

Abstract: This study aimed to examine the potential anticancer properties of Yiai Fuzheng decoction (YFD), along with its mechanism of action against triple-negative breast cancer…

Date: 2025-10-29

Mutation of conserved MHC class I cytoplasmic tyrosine affects CD8+ T cell priming, effector function, and memory response

Abstract: The cytoplasmic domain of MHC class I (MHC-I) molecules contains a single, highly conserved tyrosine residue (Y320). In previous work, we found that mice expressing a…

Date: 2025-10-29

Urinary quality of life in patients treated with prostate SBRT with intra-prostatic boost

Abstract: SBRT is a standard of care treatment for localized prostate cancer. Whole gland dose escalation remains controversial. Concomitant intraprostatic boost (IPB) may offer…

Date: 2025-10-29

Addressing sexual health needs in gynecological cancer survivors: insights from a tertiary cancer center in Jordan

Abstract: Sexual health is a crucial aspect of quality of life, yet it is rarely addressed by healthcare providers, especially in the context of gynecological cancer. Reports on…

Date: 2025-10-29

Signaling intact membrane-bound IL-15 enables potent anti-tumor activity and safety of CAR-NK cells

Abstract: Chimeric antigen receptor (CAR)-NK cells are a promising and safe alternative to CAR-T cells. However, the limited persistence in vivo restricts their clinical…

Date: 2025-10-29

Perforator mapping for head and neck reconstructive surgery: a novel personalized approach using magnetic resonance angiography based 3D models and 3D-printing

Abstract: Reconstruction of large head and neck defects in oncologic patients often requires free vascularized tissue flaps. Successful flap design and elevation depend on…

Date: 2025-10-29

Immunotherapy combined with definitive chemoradiotherapy for locally advanced unresectable esophageal squamous cell carcinoma

Abstract: The clinical value of immune checkpoint inhibitors (ICIs) in the treatment of unresectable locally advanced esophageal squamous cell carcinoma (LA-ESCC) remains under…

Date: 2025-10-29

Machine learning integration with multi-omics data constructs a robust prognostic model and identifies PTGES3 as a therapeutic target for precision oncology in lung adenocarcinoma

Abstract: Lung adenocarcinoma is the most prevalent lung cancer type, with a 5-year survival rate for advanced patients below 20%. This study aims to develop a risk model to guide…

Date: 2025-10-29

Comparison of efficacy and side effects between short-course radiotherapy and chemotherapy with or without immunotherapy in the neoadjuvant treatment for patients with locally advanced rectal cancer

Abstract: To evaluate the efficacy and safety of short-course radiotherapy (SCRT) combined with chemotherapy (ChT) with or without immunotherapy (IT) in the neoadjuvant treatment…

Date: 2025-10-29

Strategy to select nasopharyngeal cancer patients for adaptive radiotherapy

Abstract: Nasopharyngeal cancer (NPC) patients experience significant anatomical changes during radiation treatment (RT). Adaptive radiotherapy (ART) can be initiated in response…

Date: 2025-10-29