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Associations of white matter hyperintensity with frailty, sarcopenia, and nutritional risk: an analysis of an acute ischemic stroke patient database

Abstract: White matter hyperintensity (WMH), frailty, sarcopenia, and nutritional risk are prevalent and critical factors in geriatric care. This study aimed to investigate the…

Date: 2025-10-15

Serum creatinine-to-albumin ratio as a prognostic marker for short- and long-term mortality in critically ill stroke patients: a MIMIC-IV study

Abstract: Stroke remains a leading cause of mortality and disability worldwide, with critically ill patients facing particularly poor outcomes. Existing prognostic markers often…

Date: 2025-10-15

The synergistic interaction of vitamin D deficiency and insomnia on dizziness-related handicap in patients with benign paroxysmal positional vertigo

Abstract: While insomnia and vitamin D deficiency are known risk factors for BPPV, their interactive effect on the dizziness-related handicap is unknown. Given that both may…

Date: 2025-10-15

Real-world diagnostic value of integrating oral and ocular dryness testing in suspected Sjögren’s disease

Abstract: Sjögren’s disease is an autoimmune condition requiring a systemic evaluation that integrates serologic, histopathologic, and glandular assessments for diagnosis. Current…

Date: 2025-10-15

Mast cells are essential in the development of exposure-associated exercise-induced bronchoconstriction in a mouse model

Abstract: Cold air and air pollution are known triggers to induce symptoms in exercise-induced bronchoconstriction (EIB). Mast cells are hypothesized to be a key player in the…

Date: 2025-10-15

Combination of CRP and miRNA signature as a potential diagnostic strategy for Kawasaki disease

Abstract: Kawasaki disease is the leading cause of acquired heart disease in children, yet timely diagnosis remains difficult due to overlapping symptoms with other febrile…

Date: 2025-10-15

Associations of sleep disturbances in systemic lupus erythematosus with physical and psychological outcomes: a cross-sectional latent profile analysis

Abstract: Patients with systemic lupus erythematosus (SLE) frequently experience poor sleep quality. This cross-sectional study aimed to identify distinct sleep disturbance…

Date: 2025-10-15

Plasma exosomal lncRNA-related signatures define molecular subtypes and predict survival and treatment response in hepatocellular carcinoma

Abstract: Hepatocellular carcinoma (HCC) faces challenges in early diagnosis, prognosis, and treatment stratification due to molecular heterogeneity. This study aimed to establish…

Date: 2025-10-15

Distinct Arnica montana L. extracts modulate human T cell activation in different ways via differential inhibition of NF?B and NFAT pathways

Abstract: Arnica montana L. (Arnica) has a long history of use in treating inflammation and soft tissue injury, yet its immunomodulatory mechanisms remain largely unexplored. In…

Date: 2025-10-15

Changes in the malignant female reproductive system tumors disease spectrum at the Beijing obstetrics and gynecology hospital in the past 60?years

Abstract: This study aimed to evaluate the epidemiological trends in the incidence, age distribution, and pathological types of malignant female reproductive system tumors over…

Date: 2025-10-15