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Predicting the onset of internalizing disorders in early adolescence using deep learning optimized with AI

Abstract: Internalizing disorders (depression, anxiety, somatic symptom disorder) are among the most common mental health conditions that can substantially reduce daily life…

Date: 2025-10-08

Analysis of autonomic nervous function and associated symptoms in patients with peripheral vestibular disorders

Abstract: This study aimed to investigate the differential effects of vestibular lesion sites, specifically the semicircular canals and otolith organs, on autonomic nervous system…

Date: 2025-10-08

A nomogram for predicting individual risk of acute kidney injury after endovascular therapy in large vessel occlusion stroke

Abstract: This study was conducted to develop and validate a nomogram model for the early prediction of acute kidney injury (AKI) in patients with acute ischemic stroke with large…

Date: 2025-10-08

High mesothelin expression is associated with low cytotoxic T cell infiltration in pancreatic cancer

Abstract: Mesothelin (MSLN) is a cell-surface glycoprotein overexpressed in the majority of pancreatic ductal adenocarcinoma (PDAC) cases and represents a promising…

Date: 2025-10-08

Whole-exome sequencing in Saudi colorectal cancer patients reveals distinct mutational patterns and population specific pathogenic variants

Abstract: Colorectal cancer (CRC) shows significant inter-population heterogeneity in its genomic landscape, yet Middle Eastern populations are underrepresented in large-scale…

Date: 2025-10-08

Comparative short- and long-term outcomes of TOETVA, ETGUA, and COT in thyroid cancer: a propensity score-matched study

Abstract: This study aims to compare the short-term and long-term outcomes of three surgical approaches for thyroid cancer: Transoral Endoscopic Thyroidectomy Vestibular Approach…

Date: 2025-10-08

Diagnostic consistency of GLIM criteria and PG-SGA for malnutrition in patients with pancreatic cancer

Abstract: This study aimed to evaluate the diagnostic consistency between the Global Leadership Initiative on Malnutrition (GLIM) criteria and the Patient-Generated Subjective…

Date: 2025-10-08

Evaluation of hippocampus-sparing VMAT versus conventional VMAT in locally advanced nasopharyngeal carcinoma: a dosimetric and biological analysis

Abstract: Radiation-induced hippocampal damage poses a risk of cognitive decline following radiotherapy. Existing international guidelines for nasopharyngeal carcinoma (NPC)…

Date: 2025-10-08

Major adverse kidney events among chronic kidney disease patients with vitamin D deficiency

Abstract: This study aimed to evaluate the association of vitamin D deficiency (VDD) and major adverse kidney events (MAKEs) among patients with chronic kidney disease (CKD). We…

Date: 2025-10-07

Threshold effect of visceral adiposity index on suicidal ideation: a mediation analysis through fasting blood glucose

Abstract: The complex interplay between visceral adiposity and mental health outcomes, particularly suicidal ideation, remains a critical yet understudied area. This…

Date: 2025-10-07