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Administration of statins is correlated with favourable prognosis in lung cancer patients receiving immune checkpoint inhibitors

Abstract: Statins are commonly used for cardiovascular diseases and recent studies have supported their anti-cancer role in numerous human malignancies. This study aims to…

Date: 2025-10-06

Trends in liver cancer burden in China and G20: a comparative analysis using GBD 2021

Abstract: To compare liver cancer trends and risk factors in China with those in G20 countries (1990–2021) to inform prevention and resource allocation. GBD 2021 data for liver…

Date: 2025-10-06

Homologous recombination deficiency in breast cancer: genomic characteristics, clinical implications, and predictive value in neoadjuvant therapy

Abstract: Homologous recombination deficiency (HRD) significantly influences breast cancer development. HRD-positive breast cancer is more sensitive to DNA-targeting cytotoxic…

Date: 2025-10-06

Comparative analysis of external beam radiotherapy versus portal vein stent implantation combined with local and systemic therapy in hepatocellular carcinoma patients with portal vein tumor thrombus: a real-world retrospective study

Abstract: To compare the effectiveness and safety of External Beam Radiotherapy (EBRT) versus Portal Vein Stent Implantation (PVSI) when combined with local interventional therapy…

Date: 2025-10-06

Development and validation of a nomogram for predicting postoperative hypocalcemia in patients undergoing surgery for differentiated thyroid cancer

Abstract: This study aimed to identify risk factors for hypocalcemia following differentiated thyroid cancer (DTC) surgery and develop and validate a nomogram model to predict its…

Date: 2025-10-06

Anti-HLA antibodies bound to monocytes altered antibody-mediated platelet phagocytosis and led to mild thrombocytopenia

Abstract: In fetal and neonatal alloimmune thrombocytopenia (FNAIT), maternal antibodies react with alloantigen expressed on fetal platelets, leading to their clearance via…

Date: 2025-10-03

Efficacy and safety of the third-generation tyrosine kinase inhibitor Olverembatinib in relapsed and persistent minimal residual disease positive Philadelphia chromosome-positive acute lymphoblastic leukemia patients

Abstract: This study aimed to evaluate the efficacy of Olverembatinib in patients with relapsed and persistent minimal residual disease-positive Philadelphia chromosome-positive…

Date: 2025-10-03

Improvement of revised international staging system risk stratification in patients with newly diagnosed multiple myeloma using a high bone marrow plasma cell percentage: a real-world study in China

Abstract: Multiple myeloma (MM) is a heterogeneous malignant plasma cell neoplasm. A significant increase in the bone marrow plasma cell percentage (BMPC%) may adversely affect…

Date: 2025-10-03

Development and testing of an online course on the second victim phenomenon: a three-dimensional evaluation and proof of concept

Abstract: The Second Victim Phenomenon (SVP) refers to the emotional, psychological, and professional consequences healthcare professionals (HCPs) may face following adverse…

Date: 2025-10-03

Treatment of benign lesions of the proximal femur in young pediatric patients using adult 3.5 mm proximal humerus locking plates

Abstract: This study aimed to assess the efficacy of using adult 3.5 mm proximal humerus locking plates (PHLPs) for treating benign proximal femur lesions in skeletally immature…

Date: 2025-10-03