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Evaluation of real-world follow-up methods and their association with adherence and safety in adjuvant breast cancer therapy: a retrospective study

Abstract: To compare the associations between different follow-up management methods—telephone, WeChat, and mini-program—and treatment compliance, safety, quality of life, and…

Date: 2025-09-30

Yiai Fuzheng decoction inhibits triple-negative breast cancer by remodeling the immune microenvironment

Abstract: This study aimed to examine the potential anticancer properties of Yiai Fuzheng decoction (YFD), along with its mechanism of action against triple-negative breast cancer…

Date: 2025-09-30

Mutation of conserved MHC class I cytoplasmic tyrosine affects CD8+ T cell priming, effector function, and memory response

Abstract: The cytoplasmic domain of MHC class I (MHC-I) molecules contains a single, highly conserved tyrosine residue (Y320). In previous work, we found that mice expressing a…

Date: 2025-09-30

Urinary quality of life in patients treated with prostate SBRT with intra-prostatic boost

Abstract: SBRT is a standard of care treatment for localized prostate cancer. Whole gland dose escalation remains controversial. Concomitant intraprostatic boost (IPB) may offer…

Date: 2025-09-30

Addressing sexual health needs in gynecological cancer survivors: insights from a tertiary cancer center in Jordan

Abstract: Sexual health is a crucial aspect of quality of life, yet it is rarely addressed by healthcare providers, especially in the context of gynecological cancer. Reports on…

Date: 2025-09-30

Signaling intact membrane-bound IL-15 enables potent anti-tumor activity and safety of CAR-NK cells

Abstract: Chimeric antigen receptor (CAR)-NK cells are a promising and safe alternative to CAR-T cells. However, the limited persistence in vivo restricts their clinical…

Date: 2025-09-30

Perforator mapping for head and neck reconstructive surgery: a novel personalized approach using magnetic resonance angiography based 3D models and 3D-printing

Abstract: Reconstruction of large head and neck defects in oncologic patients often requires free vascularized tissue flaps. Successful flap design and elevation depend on…

Date: 2025-09-30

Immunotherapy combined with definitive chemoradiotherapy for locally advanced unresectable esophageal squamous cell carcinoma

Abstract: The clinical value of immune checkpoint inhibitors (ICIs) in the treatment of unresectable locally advanced esophageal squamous cell carcinoma (LA-ESCC) remains under…

Date: 2025-09-30

Spectrum of care approach to animal shelter management of feline infectious peritonitis complicated by feline leukemia virus

Abstract: Feline infectious peritonitis (FIP) occurs most commonly in multi-cat environments such as animal shelters. FIP is often suspected based on compatible history,…

Date: 2025-09-29

Lithospermum erythrorhizon extract alleviates immunosuppression via MAPK signaling pathway

Abstract: Lithospermum erythrorhizon extract (LEE), rich in shikonin and its derivatives, has been traditionally valued for anti-inflammatory and wound-healing properties. This…

Date: 2025-09-29