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Impact of adjuvant chemotherapy delay on overall survival in early-stage breast cancer: a retrospective analysis

Abstract: In Early-Stage Breast Cancer (EBC), there is no clear consensus on the ideal window for initiation of adjuvant chemotherapy from the time of definitive surgery.…

Date: 2025-09-19

The predictive value of serum MHR combined with classical metabolic syndrome components in the first trimester for gestational metabolic syndrome: a prospective cohort study in China

Abstract: The objective of the study was to investigate the relationship between inflammatory markers, the serum monocyte-to-high-density lipoprotein cholesterol ratio (MHR) in…

Date: 2025-09-19

Elevated mitochondrial DNA copy number in euthyroid individuals with impaired peripheral sensitivity to thyroid hormones

Abstract: The role of thyroid hormone sensitivity in metabolic and neoplastic diseases is well recognized, however, its association with mitochondrial DNA copy number (mtDNAcn) in…

Date: 2025-09-19

12-month outcomes of GLP - 1 in severe pediatric obesity: real-world data

Abstract: Real-world data on liraglutide for pediatric obesity is limited, especially in public healthcare systems of low- and middle-income countries. To evaluate the real-world…

Date: 2025-09-19

Impaired thyroid hormone sensitivity is associated with the degrees of fatty infiltration in metabolic dysfunction associated steatotic liver disease

Abstract: As a chronic disease, MASLD seriously endangers human health and has a complex pathogenesis. Thyroid hormones (THs) play significant roles in this process. We aimed to…

Date: 2025-09-19

Beyond metropolises: artificial intelligence awareness and educational needs among medical students in a developing country

Abstract: While artificial intelligence (AI) is rapidly transforming healthcare, medical curricula have not fully adapted to this transformation, particularly in developing…

Date: 2025-09-19

Association between red blood cell distribution width and encephalitis based on the pediatric intensive care unit database: a cross-sectional study

Abstract: Encephalitis is an inflammatory disease of the brain parenchyma that continues to affect populations worldwide, with high morbidity and risk of long-term sequelae. Early…

Date: 2025-09-19

Analysis of the current transition readiness of adolescent patients with kidney disease and the factors influencing it

Abstract: This study aimed to investigate the transition readiness of adolescent patients with kidney disease to understand their readiness status and ability to transition to…

Date: 2025-09-19

Unpacking the cost implications of diagnosis-related groups reform for lumbar disc herniation patients in Chinese medicine: a closer look at evidence from China

Abstract: Lumbar disc herniation (LDH) presents a significant economic burden globally, worsening in China due to an aging population. Traditional Chinese Medicine (TCM) offers…

Date: 2025-09-19

The effect of guideline-directed medicine on patients with new-onset heart failure following acute myocardial infarction

Abstract: To investigate the impact of guideline-directed medical therapy (GDMT) during hospitalization on the prognosis of patients with heart failure (HF) episode complicating…

Date: 2025-09-19