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Targeting IL-3R? on tumor-derived endothelial cells blunts metastatic spread of triple-negative breast cancer via extracellular vesicle reprogramming

Abstract: The lack of approved targeted therapies highlights the need for new treatments for triple-negative breast cancer (TNBC) patients. Interleukin-3 (IL-3) acts as an…

Date: 2023-07-25

PPDPF promotes lung adenocarcinoma progression via inhibiting apoptosis and NK cell-mediated cytotoxicity through STAT3

Abstract: Lung cancer is the most common malignancy and the leading cause of cancer death worldwide, and lung adenocarcinoma (LUAD) is the most prevalent subtype. Considering the…

Date: 2023-07-25

A Nomogram-Based Model for Predicting the Risk of Severe Acute Cholangitis Occurrence

Abstract: Acute cholangitis is one of the common clinical abdominal conditions, which frequently presents an emergency, due to partial or complete biliary obstruction (by bile…

Date: 2023-07-25

Antimicrobial Resistance and Virulence Gene Profile of Clinical Staphylococcus aureus: A Multi-Center Study from Ethiopia

Abstract: Staphylococcus aureus is a part of the normal skin flora and commonly colonizes the nose, respiratory tract, and skin. S. aureus also causes a wide spectrum of…

Date: 2023-07-25

Differential Recognition of Sporothrix schenckii, Sporothrix brasiliensis, and Sporothrix globosa by Human Monocyte-Derived Macrophages and Dendritic Cells

Abstract: Sporotrichosis is a subcutaneous mycosis that affects humans and other mammals. Its etiological agents are members of the Sporothrix pathogenic clade, and currently, the…

Date: 2023-07-25

Adherence to Atrial Fibrillation Better Care (ABC) Pathway Management of Chinese Community Elderly Patients with Atrial Fibrillation: A Cross-Sectional Study

Abstract: Atrial fibrillation (AF) is a type of supraventricular tachyarrhythmia caused by ineffective atrial contraction that results from uncoordinated atrial electrical…

Date: 2023-07-25